Hilton, 32, jetted to the South American country to open one of her fashion stores in the capital city of Bogota, reported Contactmusic.
"At the Children's Hospital in Colombia today visiting the kids. Loved spending time with them. Such precious angels," she posted on Twitter and also uploaded pictures from the hospital visit.
Hilton's boyfriend River Viiperi, who accompanied the socialite on the visit, added, "Just went with my gorgeous blondie Paris Hilton to give some presents to the kids from the children's hospital.