The 'Star Trek' actor will play a Stephen Colbert-type character as a British TV host of a cable news show. The series - to air on Starz - will be produced by MacFarlane and Bored to Death's Jonathan Ames, reported Digital Spy.
'Blunt Talk' has been given a straight-to-series order and will run for 20 episodes over two seasons.
Stewart's TV host Walter Blunt is a borderline-alcoholic who presents a nightly interview show and deals with his network bosses, staff and family.
The show will premiere in 2015.