The show, which will be a part of his "Out There Tour", will mark his first time making a stop in the city since his sold-out two-night concert back in 2010.
Tickets go on sale on May 1, reported Ace Showbiz.
McCartney is currently touring Japan and South Korea.
In addition to the Philly date, the 72-year-old British musician is expected to return to the US for appearances at Firefly Festival on June 19 and Lollapalooza on July 31.