The 38-year-old actress teamed up with the Spanish-Italian musician on track Decirnos adios (To Say Goodbye), which was composed by her brother Eduardo Cruz, reported Daily Star.
She has now combined her acting and singing skills for her appearance in the black and white promo for the song, which features a tousled-hair Cruz singing passionately behind a rain-soaked window.
"Penelope sings fabulously and, above all, she has a lot of personality in her voice and enjoys it a lot. Something that you can't say about everyone," said Bose, who also stars in the video.