Chasing a stiff target of 161 runs, Sunrisers rode on Perera's unbeaten knock off 57, which came of just 32 balls, to start the main tournament with a win that came with three balls to spare. He struck four fours and as many sixes.
Perera's knock meant Sunil Narine's remarkable spell of 4/9 in 4 overs and Darren Bravo's 44-ball 66 went in vain at the Punjab Cricket Association Stadium.
The 24-year-old Perera managed a boundary off Ravi Rampaul to bring it down to seven off six. Legspinner Karn Sharma, who surprisingly did not get to bowl, made up with the bat as he struck Navin Stewart for a for and the winning six, a pull over deep midwicket, to seal it for Sunrisers.
Sunrisers started the chase in earnest with captain Shikhar Dhawan at the helm. But, 25 balls into the innings, the hosts lost their first wicket in Parthiv Patel as Narine struck with his first delivery, having the batsman caught at short third man.
J P Duminy and Hanuma Vihari added 25 runs for the third wicket before the experienced South African left-hander was run out by Rampaul in what was another blow for Sunrisers.
What hurt the Sunrisers was that their top-three batsmen got out after getting starts. Chasing a challenging target on a pitch that had some dampness due to rain, the Sunrisers' top-half needed to do more.