"Phillander has undergone treatment at our hospital. He was treated for a multiple ligament injuries on his left ankle and has been plastered," Hosmat Medical Director Dr Ajit Benedict Royan told PTI here.
"Therefore he will be out of action from playing cricket for next six weeks. He may fly back to South Africa also," he added.
Philander twisted his left ankle during a warm-up football game and was carried back by the support staff after he was seen writhing in pain.
"He (Vernon) limped off the field ... It might be bad ...," Villiers added.
With Dale Steyn too all but ruled out of the second Test due to a groin strain, Philander's injury will leave South Africa with just two frontline quicks in their attack - Kagiso Rabada and Morne Morkel.
South Africa are 0-1 down in the four-match Test series against India. The visitors lost the first Test by 108-run at Mohali.