Hawaii News Now reports that the plane crashed today.
Federal Aviation Administration spokesman Allen Kenitzer says the plane crashed due to "unknown circumstances" while on its way to the Molokai Airport.
Kentizer says at least two people were aboard the plane when it crashed about 6 kilometres west of the airport.
Officials were notified by the Molokai air traffic control tower that communication with the plane was lost.
The Maui Fire Department, Federal Aviation Administration and National Transportation Safety Board are investigating the crash.