Researchers at the University of Missouri have used the monogamous, biparental California mouse species to prove that offspring born to parents who are exposed to widely prevalent endocrine-disrupting chemicals such as Bisphenol-A receive decreased parental care by both the mother and father.
Scientists believe results could have relevance to human parenting as well.
The California mouse is used as a model for examining parental behaviours because they are monogamous and, much like humans, both male and female partners contribute to child-rearing.
Impaired care could lead to adverse consequences for the young and, since brain regions and hormones regulating biparental behaviours appear to be similar across species, this study may have human implications.
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"Endocrine-disrupting chemicals like BPA mimic the steroid hormones that establish the 'circuitry' for the adult female brain during early development, but little was known about how this chemical might affect the father's behaviour," said Cheryl Rosenfeld, associate professor of biomedical sciences in the College of Veterinary Medicine at MU.
Researchers developmentally exposed female California mice to one of three diets.
One contained BPA, the second contained concentrations of EE and the third was free of endocrine disruptors. Likewise, males were developmentally exposed to the same three diets.
Then, the male and female mice were randomly paired. Since California mice are monogamous, one male was paired with a single female for the duration of the study.
"Likewise, we found that developmental exposure of males and females to these endocrine-disrupting chemicals resulted in their spending more time out of the nest and away from their pups, further suggesting that biparental care was reduced," Rosenfeld added.