The arrests were made near Sahajipur railway crossing on Amethi-Pratapgarh road, SP Amethi Hira Lal said.
The accused had allegedly murdered a truck driver and looted a loaded truck on the night of October 21-22 near Kanaksinghpur on Amethi-Musafirkhana road under police station Munshiganj.
The accused have confessed to their involvement in the crime, Lal added.
Two country-made pistols, four live cartridges, a knife and three mobile sets were recovered from their possession, he said.
The goods of the loot, including plastic pipes and sockets, worth Rs 8 lakh were recovered from the culprits, the SP said, adding the accused were wanted in many cases.
The SP has announced a cash award of five thousand rupees for the police team.