More than 5,000 police personnel including from Armed Reserve wing have been deployed for the bandobust, police said.
The Gujarat Chief Minister is delivering the 2013 Nani Palkhivala memorial lecture at the University of Madras's Centenary Auditorium and will also be releasing BJP leader Arun Shourie's book 'Self-deception: India China policies.'
The police have sanitised the Madras University Centenary Hall and the entire campus to ensure pool proof security.
Security has also been beefed up at the state unit BJP office where Modi would meet office bearers.
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Police have been checking vehicles in the city and have been conducting searches in lodges and hotels to rule out presence of anti-socials and suspicious elements.
Asked on security preparations, a top police official said "everything has been done in accordance with the protocol for VVIPs with high security risk."
The BJP has organised a reception for Modi at the Chennai Airport. Party workers from Chennai, Kanchi and Tiruvallur Districts are expected to welcome the Gujarat strongman.
This is Modi's second visit to Tamil Nadu in less than a month. On September 26, he addressed a public meeting in Tiruchirappalli.