While Francis remains enormously popular among most rank-and-file Catholics, a small but vocal group of conservatives who have never much cared for his radical agenda have grown increasingly strident in criticising the pope now that there is little doubt left about his priorities.
They have taken aim at the just-concluded synod on family issues, where the divisive issue of Communion for the civilly remarried took center stage.
They have raised alarm at Francis' call for a more decentralised church and his loosening of the Vatican's marriage annulment process.
The Remnant, a small, traditionalist US newspaper, last week penned an open letter begging Francis to change course or resign, arguing that his papacy was "causing grave harm to the church." Organisers say a few thousand people have signed onto the petition.
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"You have given many indications of an alarming hostility to the church's traditional teaching, discipline and customs, and the faithful who try to defend them, while being preoccupied with social and political questions beyond the competence of the Roman Pontiff," the newspaper said.
To put it more simply: "Many people in the Vatican want Francis dead," said Francesca Chaouqui, the woman at the heart of a leaks scandal currently convulsing Francis' Vatican.
In an interview last weekend with Italy's La Stampa newspaper, Chaouqui said Francis' in-house reforms and nominations have emboldened his enemies, many of whom were in the Vatican when Francis was archbishop of Buenos Aires and had a less-than-pleasant relationship with Rome.
Some of these cardinals and bishops are openly resisting his reforms while others inside and out of the Vatican are simply waiting out his pontificate under the argument that popes come and go but the Curia remains.
He said he doesn't see the dust settling until the next conclave, "which lots of conservative Catholics want to happen as soon as possible.