Pope Francis arrives in Mozambique on Wednesday at the start of a three-nation tour of Indian Ocean African countries hard hit by poverty, conflict and natural disaster.
He is expected to be welcomed by tens of thousands during his visit, which will culminate with a mass on Friday at the giant Zimpeto stadium in the seaside capital Maputo.
Pope John Paul II was the last pontiff to visit Mozambique in 1988. In a video message recorded ahead of the trip, Pope Francis stressed the need for "fraternal reconciliation in Mozambique and throughout Africa, which is the only hope for a solid and lasting peace".
The pope is expected to address the country's fragile peace process, the devastation caused by two back-to-back cyclones early this year, and the upcoming general election.
The three-day tour comes a month after the Mozambique government signed a historic peace treaty with the former rebel group Renamo, which is now the main opposition party.
The 16-year civil war devastated the former Portuguese colony and Renamo has never completely disarmed.
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The pope may also address the issue of extremism in northern Mozambique where jihadist attacks have claimed more than 300 lives over two years.
The visit will be a good omen for a country in "crisis," said Jaime Taimo, a 21-year-old student.
"With his arrival I see things are going to change... in the sense that we could live peacefully again since we've been living in constant conflict," he said.
"His arrival can bring good things."