During his visit to Milan yesterday, better known for football, fashion and luxury, the Argentine pontiff put the spotlight on those less fortunate.
Francis's first stop was at the Case Bianche (White Houses), a run-down collection of concrete tower blocks from the 1970s on the edge of the wealthy city.
"It is a symbolic choice. The pope wanted to arrive at the heart of Milan by passing first through the outskirts," parish priest Augusto Bonora told AFP, saying the parishioners were "wildly excited" when they heard that Francis would be dropping by.
With its dirty stairwells, broken mailboxes and defective lifts, the neighbourhood has become "a little ghettoised", said Mirella, 68, whose son lives on the estate in one of the forgotten corners of the country's economic capital.
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Bonora said that "like all suburbs, it's been somewhat forgotten by those in charge," but he insisted there were social programmes to help the young and care for the elderly.
After visiting the families, the pontiff performed a blessing near a small Virgin of Lourdes sanctuary.
He thanked the crowds for gifts including a photo of the local Virgin of Lourdes statue, which was recently restored.
"As your Madonna was restored, so the Church always needs to be restored," he added.
Francis' visit is "a unique occasion. Many people, non-Christians included, came to ask for passes (to attend the blessing)," said Cesare Nera, who lives in the area and helped with the preparations.
After a meeting with religious leaders, Francis pronounced the Angelus prayer in front of the Gothic Cathedral in Milan's historic centre.
Then at the 19th-century San Vittore prison, Francis sat down with 100 inmates and staff for a private lunch of risotto, escalope Milanese and panna cotta prepared by the prisoners.