"The Holy Father has taken into consideration the idea of carrying out a leg to Cuba on the occasion of his upcoming visit to the United States" between September 22 and 27, Vatican spokesman Federico Lombardi said in a statement.
The 78-year-old leader of the world's Roman Catholics confirmed late last year that he would visit the United States to take part in a Catholic Church congress in Philadelphia.
During the trip, he will also address the United Nations in New York, become the first pontiff to address the US Congress and will meet with US President Barack Obama at the White House.
A survey by the Pew Research Center released in March showed that 90 per cent of Catholic Americans thought well of the pontiff, including 57 per cent who held a "very favourable" view of him.