The late November visit comes as western Rakhine state is devoured by communal violence that has sent unprecedented numbers of Rohingya fleeing into neighbouring Bangladesh.
Myanmar's army is accused of using a crackdown on militants to expel its Muslim Rohingya population -- a persecuted minority the Pope has previously called "brothers and sisters".
Any comments seen to support the Rohingya could provoke a strong reaction from hardline Buddhist clerics and a Buddhist-majority public aggrieved at global support for the Muslim group.
A spokesman for the Catholic Church in Myanmar said it was unclear whether the Pope would address the Rakhine crisis during his November 27-30 trip.
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"We don't know yet what will be his speech... but he is coming for the sake of the country and he will be talking about peace," Father Mariano Soe Naing, a spokesman for the Catholic Bishop's Conference of Myanmar, told AFP.
"There won't be any interfaith meetings because of the lack of time," he said, although he will meet with the main Buddhist authority.
Myanmar and the Vatican only established full diplomatic relations in May, shortly after de facto leader Aung San Suu Kyi met Pope Francis during a European tour.
That visit was overshadowed by her country's treatment of the Rohingya, who are denied citizenship by the state and have previously been displaced in huge numbers by communal violence and army campaigns.
Only weeks before his meeting with Suu Kyi, Francis described the Muslim minority as "brothers and sisters" who were were being tortured and killed for their faith.
Any repetition of that stance will put Francis at odds with many inside Myanmar, where authorities have denied committing atrocities and tried to cast the Rohingya as the villains.
Buddhist nationalist hardliners have previously vowed to protest the papal visit because of his support for the Muslim group.
This week Myanmar's government called for unity with a large inter-faith rally in Yangon, the first since the Rakhine crisis.