"Yesterday in Pakistan, Holy Easter was bloodied by an abhorrent attack," the pontiff told a crowd gathered in St Peter's Square in his Angelus blessing on Easter Monday.
"Once again, violence and heinous murder lead only to suffering and destruction."
"I appeal to the civil authorities and to all the social constituents of this nation to do everything in their power to restore safety and serenity to the population, particularly the most vulnerable religious minorities", he said.
The Vatican yesterday had condemned the attack as "fanatical violence against Christian minorities".