Altogether more than 88 per cent students voted against the VC, according to the results of the referendum conducted by the students union.
A list of four questions were being asked in the voting related to the one-and-a-half year old tenure of Lohia.
The questions were whether the VC has failed to pay due attention to the opinion of the student community, whether the consistent transfer of teachers from Presidency negatively affected the academic atmosphere and whether the autonomy of Presidency University was being curbed.
Out of the total number of 2,136 students in the state university, about 85 per cent had taken part.
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Trisha Chanda, General Secretary of the students' union, said the results clearly shows the mood in the campus.
"This will strengthen our demands for the resignation of VC," she told PTI.
Last month, a group of students had gheraoed the VC in her office for 26 hours after the police allegedly assaulted them during Chief Minister Mamata Banerjee's visit to the campus.