The Duke of Cambridge will study the course at Cambridge University for 10 weeks, Kensington Palace said today.
The studies, beginning next week, will give William a good grounding for his future role running the Duchy of Cornwall, a portfolio of land, property and investments he will inherit from his father, the Prince of Wales, when Charles becomes king.
Speaking about the course, a Kensington Palace spokesman said the Duke was "very much looking forward to it".
The spokesman said: "The executive education programme of seminars, lectures and meetings will draw on the strengths of academics across the university. It will start in early January and run until mid-March.
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"The course has been designed to help provide the Duke with an understanding of contemporary issues affecting agricultural business and rural communities in the UK."
The Duke will have 18 to 20 hours of lectures, seminars and meetings a week and is likely to write essays and to make field trips.
The costs for the course will be met privately. The programme does not lead to a formal qualification but is thought to feature continual assessment.
William gave up operational duties with the air force in September after completing a three-year tour as an RAF search and rescue helicopter pilot.
The second in line to the throne is in a transitional period and is considering options for his public service, Press Association reported.