More than 150 countries took part in a month-long conference reviewing the nuclear Non-Proliferation Treaty (NPT), which seeks to prevent the spread of nuclear weapons and technology.
But talks on a final document outlining an action plan for the next five years hit a wall yesterday over a provision on convening a conference by March 2016 on creating a Middle East nuclear-weapons free zone.
Israel, which is not a member of the NPT but attended the conference as an observer, opposed the proposal backed by Egypt and Arab countries.
US Arms Control Under Secretary Rose Gottemoeller told the NPT conference that provisions on holding the conference were "incompatible with our long-standing policies."
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Gottemoeller argued that the proposed nuclear-free zone did not stand a chance of success "absent the consent of all states involved," a clear reference to Israel's opposition.
Earlier this week, the US administration had dispatched an envoy to Israel to discuss the proposal, hoping to reach a compromise that would have salvaged the final document of the NPT conference.
The head of the British delegation to the talks, Matthew Rowland, also said the terms for convening the conference on the nuclear weapons-free zone were "a stumbling block for us."
Canada said it could not agree to the document because of the provisions that would have laid the groundwork for creating the zone banning all nuclear weapons in the Middle East.
In an eleventh-hour move, Iran, which heads the non-aligned movement, requested more time to consider the final document but the session resumed with no agreement.