"Eighty per cent of the squad has been exposed to subcontinent conditions, especially India. So, there won't be too many players who will be experiencing the conditions for the first time," said coach Hilton Mooreng.
South Africa is in a tough Group A, along with Australia, New Zealand, Sri Lanka and Ireland. But, Moreeng is confident of his team's chances of qualifying for the knock-out stage.
"From a selection point of view and the preparation we have had in the last two years, we think it is the best squad for the conditions that we will be faced with," he said.
"The fact that our first three series in the Women's Championship were in the subcontinent has helped us a lot in terms of getting players used to those kinds of conditions and pitches," Mooreng added.
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In the previous World T20 (2014), South Africa knocked New Zealand out of the quarterfinals to qualify for the semifinals for the first time ever.
Moreeng believes that he has a side that can pull off another similar upset.