By publicly voicing his readiness to take on the country's top job yesterday, the man who was once Russia's richest appears to have broken a promise to steer clear of politics which he made after being pardoned by President Vladimir Putin in December.
"I would not be interested in the idea of becoming president of Russia at a time when the country would be developing normally," he was quoted as saying by Le Monde newspaper.
The comments were made as Khodorkovsky, 51, launched an online movement dubbed Open Russia to unite pro-European Russians in a bid to challenge Putin's grip on power.
"A minority will be influential if it is organised," he said during a ceremony broadcast online from Paris.
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Khodorkovsky and his allies said political change could come quickly and insisted the time had come to think of Russia's future after Putin.
The Kremlin is still likely to find the project unsavoury, said the photogenic ex-tycoon sporting closely-cropped hair and a casual shirt.
"I expect him to be upset," Khodorkovsky said, referring to his nemesis Putin.
Russian activists and prominent emigres including Paris-based economist Sergei Guriyev and London-based businessman Yevgeny Chichvarkin -- both of whom fled the country under pressure from security services -- joined the online ceremony.
Khodorkovsky, who lives in Switzerland with his family, openly supported a Ukrainian uprising that ousted a Moscow-backed president in February, but indicated he did not want a bloody revolt for Russia.