The radiocarbon analysis, which was carried out in a laboratory at the University of Oxford, places the parchment close to the time of Prophet Muhammad, who is generally thought to have lived between AD 570 and 632.
The test has placed the parchment to the period between AD 568 and 645 with 95.4 per cent accuracy.
The Quran manuscript is part of the University's Mingana Collection of Middle Eastern manuscripts, held in the Cadbury Research Library. For many years, the manuscript had been misbound with leaves of a similar Quran manuscript, which is datable to the late seventh century.
"The radiocarbon dating has delivered an exciting result, which contributes significantly to our understanding of the earliest written copies of the Quran," said Susan Worrall, Director of Special Collections (Cadbury Research Library).
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David Thomas, Professor of Christianity and Islam at the University of Birmingham, said the author of the text may well have known Prophet Muhammad.
"According to Muslim tradition, the Prophet Muhammad received the revelations that form the Quran, the scripture of Islam, between the years AD 610 and 632, the year of his death," said Professor Thomas and Nadir Dinshaw Professor of Interreligious Relations at the University of Birmingham.
"The tests carried out on the parchment of the Birmingham folios yield the strong probability that the animal from which it was taken was alive during the lifetime of the Prophet Muhammad or shortly afterwards," Thomas said.
"This means that the parts of the Quran that are written on this parchment can, with a degree of confidence, be dated to less than two decades after Muhammad's death.