Randhawa, the 2002 Asian Tour No. 1 holed seven birdies, four of them in his last six holes, as he led by one over Thai Khrongpa Thanyakon (65) at the picturesque Alpine Golf Resort.
Lying in tied third alongside veteran Scott Barr (69) was another Indian star Rashid Khan (69) at seven-under 137, while two other rising stars Shubhankar Sharma (70) and S Chikkarangappa (72) were in tied 21st place at three-under 141.
While former PGA winner, Jason Dufner (69-69) was lying tied fifth, former Masters champion, Charl Schwartzel (77-68) rebounded from a nightmarish first round to make the cut on the line.
Indians missing the cut included Jeev Milkha Singh (72-74), Rahil Gangjee (74-74) and Himmat Rai (77-71). Randhawa, winner of eight Asian Tour titles besides one in Japan, opened with four straight pars before finding three birdies on front nine.
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His birdie spree began with back-to-back birdies on 13th and 14th and he closed with two more on 17th and 18th and moved into sole lead.
"I played too good. This is the best I've played in a long, long time. I fired on all cylinders today. My driving, second shots and putting were good. I only had one missed putt and the rest were a great round of golf," said the 42-year-old Randhawa.
A well-rested Randhawa, an eight-time Asian Tour winner but not since winning the 2009 Thailand Open, was excited to be in contention after taking a two-week break to recover from a 'tennis elbow'.