More than 500 lots of her personal possessions -- the largest collection ever offered for auction -- are being sold by the estate of her acting coach, Lee Strasberg, who died in 1982.
"Marilyn was a complex and beguiling figure in her lifetime, leaving generations of adoring fans to speculate, infer, and debate about her life," Strasberg's wife Anna said in a statement.
"What has resulted is a prismatic kaleidoscope image built upon both fact and fantasy."
"This is one of the most important and historic auctions of Marilyn Monroe ever. This diverse collection gives us a most intimate glimpse of the screen legend," said Martin Nolan, executive director of Julien's Auctions.
"Never before have there been so many important artifacts from the life and career of the much loved global icon Marilyn Monroe."
Bidders will also have a chance to buy a number of revealing documents, including a taxi receipt from 1960, tax returns, recipes and a checkbook containing filled out stubs from 1962 -- the year she died.