The sale on July 11 by Sotheby's will also include a collection of handwritten letters by the leader of the Indian Independence movement to the family of Sarat Chandra Bose, a freedom fighter and the elder brother of Subhas Chandra Bose.
"Gandhi usually refused to sit for formal photographs, let alone a portraitist, making this an extremely rare portrayal of the political leader at work. The sketch shows Gandhi writing with a look of intense concentration whilst seated on the floor, and is inscribed by him with the words 'Truth is God/MK Gandhi/4.12.'31'," the auction house said in a statement.
Gandhi stayed at Kingsley Hall at the time, a community centre in London's East End, at the invitation of one of its founders Muriel Lester who had previously stayed in Gandhi's ashram (hermitage) in India.
The pencil portrait, which was inscribed by Gandhi the day before he left Kingsley Hall, was given to a local resident who was closely associated with Kingsley Hall throughout her life and has remained in her family ever since.
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The set of handwritten letters, estimated to fetch between 23,000 and 33,000 pounds (USD 29,801 to 42,735), include key comments on the pivotal partition of Bengal in the months before Gandhi's assassination.
"Sarat Chandra Bose was one of the most outspoken critics of partition and proposed an independent united Bengal. He had his allies, but formidable enemies in Congress, as well as in the League.
"Gandhi was initially supportive of Bose's efforts, but shifted his position. He had little sympathy for Bose's vision of a socialist Bengal and, coming to see that the political forces in favour of partition were irresistible, turned instead to trying to mitigate its effects," the house said in its background to the auction lots.
Dating from the mid-1940s, the other letters in the collection affirm Gandhi's continued love for the Bose family as he recalls visits to their home in Calcutta (now Kolkata) and discusses the future of India with Amiya Nath Bose, the son of Sarat Chandra Bose, the house added.
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