The blistering onslaught has prompted outrage against the regime, with the United Nations' human rights chief saying the government was orchestrating an "apocalypse" in Syria.
The Russia-backed Syrian army and allied militia launched an offensive on February 18 to retake the last opposition bastion near Damascus.
They have since taken more than 40 per cent of the enclave, waging a devastating bombing campaign that has killed more than 800 civilians.
Heavy air strikes battered several key towns in the zone today, as Syria's government dispatched hundreds of pro-government militiamen to the front.
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The Britain-based war monitor said the reinforcements were deployed to two main battlefronts on the western side of the enclave, including the town of Harasta.
Government troops were within firing range of the key towns of Misraba and Beit Sawa today, and had taken up positions at the edges of Jisreen and Hammuriyeh.
Three civilians including one child were killed in heavy air strikes on Jisreen today, the Observatory said.
Syria's state television this morning showed a live broadcast of farmland adjacent to Misraba, with columns of smoke emerging from the town's skyline.
The bombardment has continued despite a one-month ceasefire demanded by the United Nations Security Council more than a week ago.
The council will meet behind closed doors today to discuss the failed truce, after France and Britain requested urgent talks.
UN human rights chief Zeid Ra'ad Al Hussein said the Syrian regime and its foreign allies were already planning their next "apocalypse."
Eastern Ghouta's roughly 400,000 residents have lived under government siege since 2013, facing severe shortages of food and medicines even before the latest offensive began.
Forty-six aid trucks entered the area on Monday for the first time since the offensive, but had to cut short their deliveries and leave due to heavy bombardment.
Secretary-General Antonio Guterres urged all warring sides to allow aid trucks to return for a planned second delivery to the enclave's main town of Douma tomorrow.
Linda Tom, spokesperson for the UN's humanitarian coordination office OCHA in Syria, said the aid would aim to reach 70,000 people in Douma and would include medical supplies not allowed in Monday's delivery.
Inside Eastern Ghouta today, AFP correspondents heard warplanes carrying out a barrage of strikes on the battleground towns.
Today's raids came despite a daily "humanitarian pause" announced by Russia last week that is meant to bring calm to Eastern Ghouta between 9:00 am (0700 GMT) and 2:00 pm each day.
During that pause, Moscow said, it would guarantee safe passage to civilians and rebels wishing to flee the enclave.
No Syrian civilians are known to have used the "humanitarian corridor".
The two main rebel groups in Eastern Ghouta -- Jaish al-Islam and Faylaq al-Rahman -- deny that the exit routes or the pauses have been coordinated with them.
More than 340,000 people have been killed and millions displaced in Syria since the civil war started in 2011 with the brutal repression of anti-government protests.
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