"We can't afford another four years of that (the Obama Administration). Which is what we're gonna get if we elect a big government liberal like Hillary Clinton to the White House," Republican presidential candidate Marco Rubio said.
In response to a question, the Florida Senator alleged that the mainstream media is acting as a lobbyist for Clinton.
"Last week, Clinton went before a committee. She admitted she had sent e-mails to her family saying, 'Hey, this attack at Benghazi was caused by al-Qaeda-like elements'. She spent over a week telling the families of those victims and the American people that it was because of a video. And yet the mainstream media is going around saying it was the greatest week in Clinton's campaign," Rubio said.
"It was the week she got exposed as a liar...But she has her super PAC helping her out, the American mainstream media," Rubio said amidst huge applause from the audience.
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"You want to talk about what we're going to be up against next year?...Well, let me tell you one thing that I am the only guy that has consistently fought the Clinton machine every election I was ever in over the past 26 years. And not only did I fight them, but I beat them," he said.
New Jersey Governor Chris Christie said, "I know who the pessimist is. It's Hillary Clinton. And you put me on that stage against her next September, she won't get within 10 miles of the White House. Take it to the bank."
Clinton responded through a statement that she would win the presidential elections.
"We're not going to let them demean women, deport immigrants, and destabilise our economy. We're going to fight for our families and our country - and if we do our jobs right, we're going to win this election," she said.
"The questions that have been asked so far in this debate illustrate why the American people don't trust the media," Ted Cruz said amidst applause.