Ghosh was known for his cross-dressing style and fascination for jewellery and make-up. He was also one of the ardent supporters of the LGBT community.
"His passing away will be a big loss not only to lovers of cinema and art, but a huge loss to the LGBT community," tweeted Onir, who is a self-confessed gay.
"Will be leaving Kolkata in a bit. Next time I come here there will one one warm soul missing," he added.
Ghosh, man behind films like "Chokher Bali", "Antarmahal" and "Dosar" died today following a cardiac arrest. He was 49.