A passenger bus overturned after colliding with a trailer at Harloni Mur in Mianwali district of Punjab province.
"Eighteen passengers were killed and 30 injured in the accident," a police officer said.
The injured were rushed to hospitals of Mianwali, where some of them are reported to be in critical condition.
Police said that the accident was caused due to over speeding by the bus driver.
In the second accident, five people were killed when a car fell into river Neelum at Falaka Bridge in Neelum Valley of PoK.
Road accidents are common in Pakistan. Most of the mishaps are caused by reckless driving and bad roads.