The couple, who has been married for nine years, announced their split back in February.
The R&B singer has tried to win back the actress by dedicating a song to her and declared his love for her during his recent concerts, reported Ace Showbiz.
Thicke, 37, will join other performers like Shakira and Katy Perry among others.
The singer is also up for multiple awards including Top R&B Artist, Top R&B Album and Top Hot 100 Song.