The legendary band will perform two shows here next month and a further double in New York in December. Members Mick Jagger, Keith Richards, Ronnie Wood and Charlie Watts have confirmed months of speculation, reported Sun online.
"London is super appropriate. It's a full circle because we started out in London and that's our home town.
"I think the Rolling Stones are kind of quite irreverent about (our anniversary) in a way. I don't think we take it very seriously and we joke about it really. It doesn't exactly feel like your golden wedding," Jagger said.
The band has been busy in Paris rehearsing around 60 songs from their back catalogue.
They have also been in touch with former bass player Bill Wyman, who left the band in 1992, to discuss him joining them onstage for several numbers.