The tradition goes back to ancient Greece when Hippocrates applied honey to treat wounds, and the Romans saw pollen as "life-giving".
In the past of India, China and Egypt, a resinous substance collected by bees from the buds of certain trees, known as "propolis", was popular as an antiseptic.
"The hive is the oldest and healthiest natural pharmacy," said Cristina Mateescu, director general of the Institute for Apicultural Research and Development in Bucharest.
"In my village, my great-grandmother was a healer and used products from beehives. She inspired me," Dr Mariana Stan told AFP.
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Having spent years as a conventional doctor, Stan now practises in Bucharest as a "apitherapist" -- using bee products "which give slower but longer lasting and more profound results".
In a country still infused with folk culture, several families continue to use propolis against sore throats, as well as honey and pollen to boost the immune system.
Every town in Romania has its "plafar" -- natural pharmacies selling products made from plants, honey, beeswax and propolis.
Modules on apitherapy have started to work their way into more conventional medical classes and extracts from propolis developed by the Apicultural institute into recognised medicines.
Founded in 1974, the institute employs 105 people who look after local bee colonies and sell around 30 approved products.
A new range even seeks to treat cats and dogs with bee-related products.