Ignazio Marino, the Italian capital's centre-left mayor, gave his blessing on today evening to the experiment in the Eur business district to the south of the city's historic centre.
The local council there has proposed allowing prostitution in one non-residential area with the aim of reducing the impact of a trade currently conducted on more than 20 streets in the district.
Police will be ordered to impose fines of up to 500 euros on prostitutes caught working outside of the permitted area, which will be supervised for evidence of the women involved being exploited. If the experiment proves successful, the council wants to establish up to three separate red light zones within the district.
"Eur is already the city's red light district with more than 20 streets under siege day and night," she told La Repubblica. "There are streets for transvestites, streets for very young girls, streets for male prostitution. Us residents need a bit of peace."
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Objections to the initiative have been raised by the centre-right opposition on Rome's municipal council, Church figures and even some within mayor Marino's Democratic Party (PD).
"I hope it is just a bizarre idea dreamed up to draw attention to the problem," said PD councillor Gianluca Santilli, who argued that the idea would lead to unacceptable prostitute "ghettoes."
The law does not ban the sale of sex but soliciting, pimping and operating a brothel are illegal.