Besides, euro's weakness against the US dollar overseas on eurozone concerns also put pressure on the local unit, forex dealers said.
However, a higher opening in the stock market capped the rupee's losses, they added.
Meanwhile, the BSE benchmark Sensex rose by 85.16 points, or 0.46 per cent, to 18,710.50.
The rupee had gained 16 paise to end at 53.56 against the dollar in the previous session on Thursday on rise in local equities amid fresh selling of the American currency by exporters.
The forex market remained closed on Friday on account of 'Idd-Ul-Zuha'.