"Limiting freedom of expression is not just censorship, it is also an assault on human nature," Rushdie told a news conference.
"Expression of speech is fundamental to all human beings. We are language animals, we are story-telling animals," he said, insisting that free speech was a universal principle.
"Without that freedom of expression, all other freedoms fail," he said.
Rushdie has had an Islamic death sentence hanging over his head for a quarter of a century over his 1989 book "The Satanic Verses".
More From This Section
"I always thought in a way we shouldn't need to discuss anymore about freedom of speech in the West, it should be like the air we breathe," Rushdie said.
"It seemed to me that this battle was won a couple of hundred years ago" during the French Enlightenment, he said.
"But the fact that we have to go on fighting this battle is the result of a number of regrettable, more recent phenomena," he continued, pointing to "violent threats" against writers, publishers, book sellers and translators.
His new novel, entitled "Two Years, Eight Months and Twenty-Eight Nights", is appearing almost simultaneously in English and in German translation.