The 37-year-old is currently in negotiations for the lead role, about an obnoxious French nihilist who embarks upon an obstacle-filled journey from Paris to London when he transports a stolen painting, reported Contactmusic.
"Pierre Pierre" will see Brand stumble upon a serial killer named Pigeonshit, a French policeman and his own brothel-owning mother in the politically incorrect road movie.
Todd Black, Jason Blumenthal and Steve Tisch will produce under Escape Artists along with Brian Sher from Category 5.
Jim Carrey and Jason Reitman were originally attached to the project and the initial script was penned by Edwin Cannistraci and Frederick Seton.
Charles is best known for his outrageous Sacha Baron Cohen-fronted flicks "Borat" and "The Dictator".