It was the latest and arguably most resonant salvo in an escalating and economically-bruising trade war over a bloody conflict in Ukraine that has plunged East-West relations into what some have dubbed a "new Cold War".
Russia has a long and varied history of using sudden food safety concerns as a political weapon against unfriendly states.
It has cited health grounds to ban Ukrainian products and halted imports of Georgian wine months before going to war with the Caucasus nation in 2008.
Russia responded by blacklisting nearly all US and European food imports and threatening even more drastic measures that could effectively cut off the country from Western goods for the first time since the Soviet era.
Also Read
But the most emotive attack on the United States came yesterday when Moscow health authorities locked up a McDonald's restaurant that had opened its doors in the final years of Communism and because a symbol of Russia's gradual acceptance of the West.
The federal office of the Rospotrebnadzor consumer safety watchdog took the campaign to a new level by ordering checks of McDonald's outlets stretching from the European portion of Russia across the Ural Mountains and into Siberia.
"We have a letter - it is an order from the federal (Rospotrebnadzor) service that is based on a government decree," an official at the consumer watchdog's Ivanovo district office in central Russia told Interfax.
Moscow's Kommersant business daily suggested that the authorities had no immediate complaints against Burger King because the Russian operations of the number two US fast food chain is nearly half-owned by the investment arm of the state bank VTB.
"That is why the (Moscow) restaurants were immediately closed, even though when scheduled (safety) checks are conducted, first a written warning is usually issued," the unnamed source in one of Russia's federal agencies told the paper.