The coalition has since last year operated a "memorandum of understanding" with Russia, whereby the two military forces notify each other of flights during their separate bombing campaigns to avoid accidents in the skies over Syria.
"The Russians did notify the coalition as per the memorandum of understanding for safety of flight," US military spokesman Colonel Chris Garver said.
"They informed us they were coming through and we ensured safety of flight as those bombers passed through the area and toward their target and then when they passed out again. They did not impact coalition operations in either Iraq or Syria during the time."
IS fighters are concentrated only in Deir Ezzor and not Aleppo or Idlib, Garver noted.
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Russia yesterday said it and the United States were close to joining forces in some form around Aleppo, but US officials have not confirmed this.
Garver said the Russians had provided "not a lot" of warning but that it "was enough time to make sure that we could ensure safety of flight."
The United States and various coalition partners have been bombing IS in Iraq and Syria for two years, while Russia's strikes have predominantly been in support of regime forces loyal to President Bashar al-Assad.
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