The Economic Freedom Fighters on Friday filed charges of murder, attempted murder and the conspiracy to commit murder against Deputy President Cyril Ramaphosa for the miners' deaths during a violent 2012 strike in Marikana, in the North West province.
The party also laid charges against the national police commissioner, the then police and mining ministers and the directors of the Lonmin platinum mine.
The Economic Freedom Fighters based the charges on the findings of a commission of inquiry into the killings, published last week.