The 23-year-old Indian has been struggling for the last one-and-a-half year with just one title to show in the form of India Grand Prix Gold in January.
However, she won all her matches in the Uber Cup to help India win bronze in the tournament. But her comeback at Indonesia ended in the last eight stage and Saina will be itching for a title at Australia.
Eighth seed P V Sindhu, ranked 10th in the world, will open her account against qualifier Aya Ohori of Japan, while P C Thulasi will be up against Malaysia's Jamie Subandhi in the women's singles first round at States Sports Centre tomorrow.
In the men's singles, B Sai Praneeth will be playing a qualifier in the first round, while H S Prannoy will have to overcome the challenge from eight seeded German shuttler Marc Zwiebler if he has to proceed further in the tournament.
In men's doubles, Manu Attri and Sumeeth Reddy will meet seventh seeded Chinese combo of Haifeng Fu and Nan Zhang.
Among others, Pranaav Jerry Chopra and Akshay Dewalkar will take on Singapore's Yong Kai Terry Hee and Zi Liang Derek Wong, while Alwin Francis and Arun Vishnu will square off against qualifiers.