Saina, who was ensured of the world no. 1 during her exploits at the India Open triumph, continued her rampaging run with a dominating win over Yao 21-13 21-9 in a lop-sided 30-minute women's singles match to set up a clash with another Chinese shuttler, Sun Yu, ranked 15th in the world.
After clinching successive titles last month, world no. 4 Kidambi Srikanth lost in the second round today, going down to China's Tian Houwei 14-21 18-21 in a men's singles match.
Kashyap, who slipped to world number 17 today following a dip in performance due to a spate of injuries, suffered a 10-21 6-21 defeat to world no. 1 Chen Long of China.
Prannoy, who jumped three places to 14th after his giant-killing exploits at the India Open, went down to two-time Olympic champion Lin Dan of China 15-21 14-21 in another men's singles match that lasted 52 minutes.
Commonwealth Games silver medallist Jwala Gutta and Ashwini Ponnappa, too, suffered a loss in the second round, going down fighting 23-21 8-21 17-21 to sixth seeded Indonesian pair of Nitya Krishinda Maheswari and Greysia Polii in a close to an hour match.