In becoming the first Indian woman shuttler to attain the number one spot in world rankings, Saina took over the reins from China's Li Xuerui, who slipped to third with Spain's Carolina Marin claiming the second position.
Saina, who had clinched the India Open Super Series title on March 29, was already assured of the top spot after Xuerui lost in the league stage of Delhi event and the 25-year-old Hyderabadi's closest challenger for the position, Carolina, also lost her semi-final match.
Risinng women's shuttler PV Sindhu held her ninth position.
Saina, who shuttled past former world champion Ratchanok Intanon of Thailand 21-16 21-14 in the summit clash at the Siri Fort Sports Complex had said: "I think the consistency with which I am playing is great. I reached three finals in last two months and it is not easy."
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"Titles makes me hungry. Next I hope to win more and more titles, I hope to be fit and injury free. This result will motivate me to win more titles."
In the men's category, India Open Super Series winner Kidambi Srikanth stayed at the fourth spot with China's Chen Long leading the rankings chart.