Ever since Pullela Gopichand emulated Prakash Padukone's 1980 feat in 2001, no Indian has ever laid claim to the crown with Saina being the country's only shuttler to come close to achieving that rare feat when she reached the finals at 2015 before losing to Olympic champion Carolina Marin.
Back to full fitness after putting in the hard yards following a complete recovery from the knee injury, which had broken her Rio Olympics dream, Saina is now aiming to regain her position in world badminton and will be eager to dish out a powerpacked performance at the Barclaycard Arena.
Both Saina and Sindhu have made a resounding start to the new season with titles at Malaysia Masters and Syed Modi Grand Prix Gold tournaments in January and they would now look to make a positive start to the Super Series circuit, which also includes events at India, Malaysia and Singapore.
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"I was runners-up in 2015 All England Championship but facing Carolina (Marin) was a very big task. She overpowered me and won the title. I am fine and well-trained now so I am ready to face my opponents," World No. 10 Saina said.
In the form of her life, sixth seed Sindhu will face Denmark's Mette Poulsen in the opening round and is likely to meet world No. 1 and top seed Tai Tzu Ying of Chinese Taipei at the quarterfinals if she doesn't suffer any hiccups.
In men's singles, Rio Olympics quarterfinalist K Srikanth, who is on a comeback trail after recovering from an ankle injury, will look to put his best foot forward after a pre-quarterfinal finish at the German Open last week.
Also competing at the world's oldest badminton tournament will be Swiss Open champion H S Prannoy and two-time Dutch Open winner Ajay Jayaram in men's singles event.
World No. 13 pair of Pranaav Jerry Chopra and N Sikki Reddy will face Korean combination of Yoo Yeon Seong and Kim Ha Na, while Rio Olympians Manu Attri and B Sumeeth Reddy will take on a qualifying pair.
Women's doubles pair of Jakkampudi Meghana and Poorvisha S Ram will meet Chinese Taipei combo of Hsu Ya Ching and Wu Ti Jung.