The government of Saint Helena, a British territory, said yesterday that final negotiations were underway for Comair to fly once a week from Johannesburg to a new airport due to open next year.
The Boeing 737 138-seat flight will take four and half hours in stark contrast to the five days it currently takes on an irregular boat service from Cape Town.
"This marks a very positive step for St Helena in working with an airline... Which provides an excellent gateway to the rest of the world," the island government said in a statement.
He died on the island in 1821.
Saint Helena, which now has 4,200 inhabitants, was a busy stop-over point between Europe, Asia and South Africa until steam ships and the Suez Canal changed sea routes.
Comair, which has a license agreement with British Airways, is a South African aviation company founded in 1946.