He cited Pope Francis and St John Paul II repeatedly during his speech to the Vatican conference commemorating the 25th anniversary of a landmark teaching document from John Paul on social and economic justice after the Cold War.
Sanders arrived in Rome hours after yesterday night's New York debate, saying the opportunity to address the Vatican conference was too meaningful to pass up. The roughly 24-hour visit precedes Tuesday's crucial New York primary, which Sanders must do well in to maintain any viable challenge against Clinton.
Sanders warned that youth around the world are no longer satisfied with the status quo, which includes "corrupt and broken politics and an economy of stark inequality and injustice."
"They are not satisfied with the destruction of our environment by a fossil fuel industry whose greed has put short term profits ahead of climate change and the future of our planet," he said.
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He sat next to the other main guest of honor at the Vatican: Bolivian President Evo Morales, whose is renowned for his anti-imperialist, socialist rhetoric.
As he walked through Vatican City's Perugino gate, Sanders was greeted about two dozen supporters, some of whom carried signs bearing Sanders' name.
The senator told reporters that he was honored to address the conference and admired Francis' message on the economy and the environment.
Pope Francis apologized that he couldn't personally greet participants at the Vatican conference. No meeting with Sanders was expected.