The national survey of more than 1,600 registered voters, conducted by Gravis Marketing two days before the general election, found that 75-year-old Vermont Senator would have received 56 per cent of the vote while Trump would have won 44 per cent.
The poll was commissioned and financed by outgoing Florida Congressman Alan Grayson, a Democrat who endorsed Sanders in the presidential primary, The Huffington Post reported.
The last election result that decisive was Ronald Reagan's victory over Democrat Walter Mondale in 1984.
Clinton, by contrast, lost independents 48 per cent to 42 per cent, according to exit polls.
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Although the Gravis poll did not show state-level results, it is safe to assume that any candidate with that type of lead in the popular vote would win the electoral college handily.
Of course, the poll results are an imperfect indicator of what would have occurred if Sanders had actually been on the ballot on election day.
"As we contemplate the dark days ahead, and then as we suffer through them, we Democrats should remember that it could have been entirely different. All we had to do was to elect a progressive as president just as a large majority of Americans really wanted," Grayson was quoted as saying.
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