Longtime friend Robert Duncan said Pearlman died yesterday in Novato Community Hospital in Novato, California.
Pearlman was 72 and had been in poor health since suffering a cerebral hemorrhage last year.
A New York City native, Pearlman wrote for one of the first rock magazines, Crawdaddy, in the 1960s and helped found Blue Oyster Cult.
He later managed Black Sabbath and the Dictators, and in 1978 produced the Clash's "Give 'Em Enough Rope," widely regarded as one of the greatest punk albums.