Courtesy a quarterfinals appearance at the Roland Garros, Sania earned 430 ranking points along with partner Cara Black to jump eight places in the ranking charts.
Sania and Cara had lost to eventual champions Shuai Peng and Su-Wei Hsieh.
"When I started the season this year in January, one of my goals was to better my career-best world ranking. I am happy to have achieved this today," Sania said from Birmingham, where she is gearing up for the grass court season, leading to Wimbledon championships.
India's number one singles player Ankita Raina also achieved her career-best rank, 262, with a jump of 28 places. Ankita had ended runner-up at a USD 25,000 event in Indonesia to earn 30 points.
In the ATP rankings, Somdev Devvarman dropped out of top-100 as he lot 23 places to be 119 in the singles chart. He had made a first round exit at the French Open.
In the doubles, out of action Leander Paes continued to be the highest ranked player at number 13. Rohan Bopanna was next best at number 17.