Parker, 47, will play the editor of Vogue in her guest appearance on the musical drama, reported Femalefirst.
"Sarah Jessica Parker is gonna be running Vogue.Com. That's sort of where we encounter this character, who's sort of frazzled, eccentric, hilarious. It's gonna be good," Ian Brennan, the show's co-creator and executive producer, said.
The actress' storyline sees her encounter both Rachel Berry (Lea Michele) and Kurt Hummel (Chris Colfer) in New York.