The Board chooses AIADMK's candidates for elections and the shuffle comes on a day when the Election Commission announced byelection to the RK Nagar assembly constituency on April 12.
The poll was necessitated by the demise of Jayalalithaa in December last year.
AIADMK Deputy General Secretary, TTV Dinakaran, made the announcement in a party release, which was issued with the "approval" of Sasikala.
"The Parliamentary Board has been reconstitued," with Sasikala as it Chairperson, he said even as he also was appointed as one of the members.
The previous Parliamentary Board headed by Jayalalithaa included expelled party leader and former Chief Minister O Panneerselvam and his aide E Madusudanan.